Using customized tools and databases for teaching Bioinformatics in introductory biology courses

 

Melody Neumann & Nicholas Provart

Tested Studies in Laboratory Teaching, 2006, Volume 27

Abstract

The developing field of Bioinformatics has revolutionized modern cell and molecular biology, in the research laboratory and classroom. It is important that students receive an introduction to Bioinformatics, and this is best accomplished by using bioinformatics tools to address biological questions, including a critical analysis of the output. Our second year Biology students (>1500) expressed frustration with the use of publicly available bioinformatics tools and databases, since these can be quite complicated, and frequently place a significant emphasis on sophisticated computing skills, complex statistical theory, or computational algorithms. This computer-based mini-workshop demonstrates exercises where students were able to develop a basic understanding of Bioinformatics by using customized tools and databases to solve real biological problems. Simplified bioinformatics tools containing the key features of common tools (eg. Blast and ClustalW) can be accessed from http://bio250y.chass.utoronto.ca/labs/lab_notes/lab4/newBioinf /index.htm . Pedagogical and logistical issues surrounding the implementation and improvement of Bioinformatics computer labs, particularly for large introductory courses are also addressed.

Keywords:  bioinformatics, database

Virginia Tech (2005)