Association for Biology Laboratory Education

The Creature from Beneath: An Inquiry Genetics Exercise for Introductory Non-Science Majors
 

Peggy Brickman & Cara Gormally

Tested Studies in Laboratory Teaching, 2007, Volume 28

Abstract

This lab provides non-science majors taking an introductory biology laboratory course with an opportunity to enjoy genetics in a way that they are rarely afforded –through self-guided discovery using live organisms. The challenge that engages students in this lab is to discover the genotype of “mystery mutants,” prepared C. elegans worms that have a normal phenotype. Possible hidden mutations include alleles that are incompletely dominant, autosomal recessive, X-linked recessive, or dihybrids. Students choose one of four different mystery mutants and then plan and execute genetic crosses to uncover the hidden mutation.

Keywords:  mutation, Caenorhabditis elegans, genetic crosses

Purdue University (2006)