Use of bioinformatics to investigate β-Lactamase, a mediator of β-Lactam

 

Paula Lessem

Tested Studies in Laboratory Teaching, 2009, Volume 30

Abstract

Bacterial antibiotic resistance is a major problem affecting health care today. This module investigates β-lactamase, a bacterially produced enzyme that destroys β-lactam antibiotics (penicillin, ampicillin, cephalothin for example). This module combines lecture material with laboratory experiments, computer simulations, and bioinformatics.

Keywords:  bioinformatics, antibiotic

University of Toronto, Mississauga (2008)