Towards A Deeper Understanding: Linking Mendelian Genetics With Molecular Genetics Using Web-Based Bioinformatics Tools

 

Barrette-Ng, I. H., D. MacMillan, & D. Hansen

Tested Studies in Laboratory Teaching, 2010, Volume 31

Abstract

The traditional model of teaching introductory undergraduate genetics begins with a description of classical Mendelian genetics that is followed by an abrupt transition to topics of molecular genetics. We re-evaluated this model and asked whether the teaching of Mendelian and molecular genetics could be improved by introducing an inquiry-based laboratory exercise in which pairs of students investigated a genetically-inheritable disease using basic bioinformatics tools. The implementation of this exercise in a large (>500 students), second-year undergraduate, introductory genetics course for biology majors led to a high level of student satisfaction and a more integrated introduction to classical and molecular genetics.

Keywords:  Molecular Biology, inquiry method, bioinformatics, Mendelian inheritance, information literacy, Mendelian genetics, molecular genetics

University of Delaware (2009)