Relating biochemistry to morphology using inquiry-based collaborative student research in developmental biology. Part I. Proposed experimental design

 

Hoegler, C. S. & C. F. Blando-Hoegler

Tested Studies in Laboratory Teaching, 2010, Volume 31

Abstract

This study proposes a pedagogical design that encourages students to use animal embryogenesis as a medium for relating biochemical changes to morphological events and organ differentiation. It suggests the use of inquiry-based collaboration in the laboratory of an undergraduate Developmental Biology course. Phase I of this inquiry-based collaboration introduces students to amphibian embryo culturing, protein electrophoresis and database searching using prescribed instructor exercises. In Phase II each student team develops a hypothesis and proposal about their research interest dealing with the effects of chemical or physical agents on embryogenesis. After instructor review, teams complete the project and present results. Our results suggest that this project could be implemented. Data would include mortality and morbidity rates as well as elucidating the pattern of the embryonic protein bands. The strategy and ultimate goal of this pedagogy is to build undergraduate student confidence and analytical skills to help understand the relationship between morphology and biochemistry. In addition we think this will motivate students and sustain their interest in biology beyond college.

Keywords:  PAGE, Amphibian Development, Inquiry-based Collaborative Learning

University of Delaware (2009)